Anke Dijkstra, the Netherlands

Presentation
In the past decades, the field of frontotemporal dementia (FTD) has seen great advances in understanding the genetic and molecular underpinnings of the disease. Despite these advances, effective treatment strategies remain elusive. One of the largest challenges to develop these strategies is the identification of the molecular subtypes of protein aggregation in the brain, such as TDP-43, tau and FUS, during life. If we are aware of the particular protein that aggregates in a patient, we are enabling more precise patient stratification for clinical trials. This presentation aims to explore the translational aspects of FTD, highlighting how basic scientific discoveries are being leveraged to develop novel diagnostic tools and therapeutic strategies.
Bio
Dr. Anke Dijkstra is an assistant professor at the University of Amsterdam and focuses selective vulnerability and clinicopathological presentations in FTD using human post-mortem tissue of the brain and other peripheral tissue. Her current research focus includes the in-depth characterization of selectively vulnerable neuronal population in their relationship to TDP-43 aggregation.
FTD from bench to bedside
Date: 22 Sep 2024Time: 08:00 - 08:30 CET